
Depression relief usually takes weeks, but what if it didn’t? Accelerated TMS is a newer, fast-acting brain-based treatment that aims to deliver meaningful results in days, not months—and we’re breaking down how it works, who it’s for, and how it stacks up against other options.
If you’re reading this, there’s a good chance accelerated TMS isn’t your first stop—it’s the option you’re looking at after trying things that should have helped but didn’t, at least not enough. When you’ve cycled through medications and therapy yet you’re still struggling, the search for something that actually moves the needle can feel exhausting—and urgent.
I know what it’s like to keep showing up, doing the work, trying different clinicians, different approaches, different versions of “self-care,” and still feeling stuck. When relief is slow—or nonexistent—it’s natural to want the next step to work, and to work faster. That’s why so many people are now looking into accelerated TMS for depression.
But the information out there can feel overwhelming. SAINT TMS, iTBS, accelerated schedules, multiple sessions a day—seriously, what the heck does it all mean, and more importantly, does it matter for better results? This article is here to cut through the noise.
We’ll walk you through what accelerated TMS therapy really is, how it works, who it may help, how it compares to other treatments, and what the science does—and doesn’t—say so far. No hype, no pressure—just clear, compassionate guidance.
Repetitive transcranial magnetic stimulation (rTMS or just TMS) is a noninvasive treatment that uses magnetic pulses to stimulate specific brain regions involved in mood regulation. It’s been FDA-cleared for treatment-resistant major depressive disorder (MDD) for over a decade (and more recently for obsessive compulsive disorder, aka, OCD, and smoking cessation).
Standard TMS for depression typically targets the left dorsolateral prefrontal cortex (l-DLPFC) using high-frequency stimulation (often 10 or 18 Hz), delivered once daily for between 20-45 minutes over six weeks. It’s two seconds on, and a pause of less than a minute. This pattern of stimulation acts directly on the neural circuits linked to depression. With this on-again, off-again stimulation TMS can help relieve symptoms, especially when medications haven’t worked.
Common types of TMS include:
Traditional TMS works really well for depression, but the daily, weeks-long schedule can be tough to manage, especially if you’re juggling work, childcare, or transportation.
Accelerated TMS solves that problem by delivering more than one TMS session per day, compressing weeks of treatment into days. The goal? Faster symptom relief without sacrificing effectiveness, and in some cases, potentially improving outcomes.
In recent years, the FDA has cleared several accelerated TMS protocols:
Early research suggests accelerated TMS treatment can significantly reduce symptoms of depression (and OCD), with some studies showing patients with depression improving more quickly than with standard TMS treatment schedules. That said, this field is still evolving, and experts are actively refining how best to deliver it.
Case in point: scientists and clinicians continue to refine techniques to target the right brain area for treatment. Most TMS protocols aim for the DLPFC, but there are several ways to find that spot:
While MRI-guided approaches may theoretically improve precision, the science isn’t settled. “In some situations, imaging can be helpful but not necessary,” says Dr. Hanlon. For example, during longer TMS sessions, “small head movements or coil shifts can affect accuracy,” she says. In this case, a structural MRI can come in handy. Still, there are plenty of workarounds.
“Many systems address this in other ways, such as using wider electric fields or helmet-like designs that allow natural movement while maintaining consistent targeting,” Dr. Hanlon explains. Meaning, advanced brain imaging isn’t required for successful accelerated TMS. “In most cases, standard targeting methods combined with modern TMS devices work very well,” she says. Outcomes have steadily improved as technology advances and clinicians gain experience, she adds.
Used in certain accelerated TMS protocols like SAINT, intermittent theta burst stimulation (iTBS) is a rapid-fire stimulation pattern that mimics the brain’s natural rhythms. It allows clinicians to deliver effective treatment in a fraction of the time.
While not all accelerated protocols rely exclusively on iTBS, it’s a favorite because it’s fast: sessions last 160 seconds to deliver 600 pulses, compared to 20–30 minutes for traditional TMS to deliver an equivalent dose.
iTBS works by increasing neural excitability and strengthening synaptic connections—effects that can last well beyond the session itself. Research suggests that higher total pulse doses and more frequent sessions may lead to stronger clinical benefits.
The FDA-cleared Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT) protocol is currently the most intensive accelerated TMS approach for MDD.
Here’s what makes it stand out:
In a small clinical study, 79% of patients reached remission during the four-week follow-up after just five days of SAINT treatment for depression—an eye-opening result that continues to fuel interest and research.

The results to date are very promising. “Accelerated TMS has been shown to be highly effective for treating depression, with the main advantage being that results can be achieved in a much shorter time frame than traditional TMS schedules,” says Dr. Hanlon.
Here’s what the research tells us so far.
SAINT delivers some of the most striking early results. In a small clinical study, 79% of patients reached remission during the 4-week follow-up after just five days of treatment. In another SAINT study, 70% entered remission one week later, though durability dropped over time—about 33% remained in remission for depression at 12 weeks. In other words: fast relief, with ongoing questions about how long benefits last. However, with repeated treatments, patients were able to sustain or remission with no decrease in effect over time.
Results here are also impressive. In an early case report, sequential bilateral theta burst deep TMS delivered strikingly fast results: one patient saw a 94% drop in depressive symptoms in just three days. Across patients, about half improved, and nearly 28% reached full remission in roughly 20 sessions—fewer than the usual 25–30 needed with traditional protocols.
Another retrospective study–co-authored by Radial’s chief medical officer and co-founder Owen Scott Muir, MD, DFAACAP–found that accelerated Deep TMS using the H1 coil led to an 80% response rate and 51% remission, with improvement starting as early as day 3 or 4. Even more encouraging, 93% of responders maintained benefits for six months.
Accelerated deep TMS also stacks up well against the traditional version. In one study, also co-authored by Muir, both accelerated and standard deep TMS protocols significantly reduced depression symptoms in people with major depressive disorder.
Similarly, a large multicenter trial of BrainsWay’s SWIFT Deep TMS protocol—including treatment at Radial—showed it “worked just as well as the standard deep TMS protocol,” but with “far fewer clinic visits,” says Dr. Hanlon, one of the authors of the study . “Response rates were nearly 88%, and remission rates were about 78%,” comparable to the standard protocol, she says. The key difference? Speed. Patients reached remission faster, with a median time of 21 days versus 28 days on the traditional schedule.

Despite the strong early data, accelerated TMS is still a developing field. Many studies so far have small sample sizes, varying methods, and different targeting approaches, which makes it hard to draw firm, universal conclusions.
Researchers are still figuring out important details—like the ideal number of sessions per day, the best spacing between sessions, and the total dose needed for lasting results. Until larger, more standardized studies are completed, experts agree the evidence is encouraging but evolving. Ongoing research will help clarify how to optimize treatment and how lasting the results truly are.
Accelerated TMS is a promising, science-backed option for depression, but it’s not the only one. Medications, standard TMS, and other therapies all have a role. The real question is how accelerated TMS stacks up in terms of speed, effectiveness, side effects, and access.
“Compared with other depression treatments, accelerated Deep TMS” and other accelerated protocols offer “a non-medication option with minimal side effects and no anesthesia,” says Dr. Hanlon. Accelerated TMS also boasts “strong clinical outcomes, faster relief, and a more convenient treatment schedule,” she adds.
Let’s break it down.
Same idea, very different pace. Both treatments stimulate mood-related brain circuits using magnetic pulses, but accelerated TMS compresses the timeline.
Treatment timeline
Effectiveness
Side effects
FDA status
Insurance coverage
Important caveat: While early results are encouraging, fewer studies directly compare accelerated and standard TMS head-to-head. Researchers are still refining the “sweet spot” for sessions per day, spacing between sessions, and total pulse dose.
Antidepressants are often the first stop, but they’re not the best fit for everyone.
Treatment timeline
Effectiveness
Side effects
FDA status
Insurance coverage

Like accelerated TMS, fast-acting medications ketamine and esketamine (a derivative of ketamine) work quicker than traditional antidepressants, but they work differently.
Treatment timeline
Effectiveness
Ketamine and esketamine can work fast—often within 24 hours. Studies suggest esketamine leads to about 37–40% remission and 48–60% response after the first month. The catch? The antidepressant effect often fades, making maintenance treatments common.
Accelerated TMS shows higher remission rates in treatment-resistant depression—up to 79% in SAINT studies and 80% response with accelerated Deep TMS. In one observational, head-to-head study, accelerated TMS produced faster and stronger responses at one month compared to esketamine.
Side effects
FDA status
Insurance coverage
Electroconvulsive therapy (ECT) works by delivering controlled electrical stimulation to trigger a brief seizure while you’re under general anesthesia. For people who are suicidal, can’t tolerate medications, or haven’t responded to anything else, ECT is still considered the gold standard.
That said, power comes with trade-offs. “More intensive options like ECT may act faster for severe cases,” says Dr. Hanlon, “but [they] involve anesthesia and greater side-effect concerns.”
Treatment timeline
Effectiveness
For moderate to severe depression, ECT is very effective, with a response rate of 73% and remission rate of 51%. In a minority of people with treatment resistant depression, it can produce a rapid (think: almost immediate) reduction in depressive symptoms and suicidal ideation. However, many people with treatment resistant depression don’t respond until after 6–8 treatments spread over several weeks.
Accelerated TMS shows strong remission and response rates in treatment-resistant depression—up to 79% remission in SAINT studies and 80% response with accelerated Deep TMS.
While one study found ECT reduced depression scores more than standard TMS, it didn’t compare ECT to accelerated TMS, making direct conclusions tricky.
Side effects
FDA status
Insurance coverage
Most insurance plans at least partially cover ECT. Coverage for accelerated TMS is expanding but remains plan-dependent, typically requiring prior treatment failure and documentation of medical necessity.
Accelerated TMS isn’t a replacement for every depression treatment, but it offers a compelling option for people who want faster relief, fewer side effects, or a non-medication approach. As research evolves and access expands, it’s becoming an increasingly important part of the depression treatment landscape.
When it comes to TMS therapy, safety is one of its biggest selling points. “Yes, accelerated TMS is generally very safe,” says Dr. Hanlon. It’s “well tolerated, and most people are able to return to their normal activities right after a session,” she adds.
One major advantage of TMS overall is that it’s targeted and localized. Because it stimulates specific brain circuits rather than affecting the whole body, it avoids many of the systemic side effects commonly associated with medications.
That said, no medical treatment is completely risk-free. The reassuring part? Most side effects are mild, temporary, and similar to standard TMS, according to Dr. Hanlon. Side effects “can include scalp discomfort during treatment, headaches, facial muscle twitching, or feeling tired later in the day,” she says. These symptoms often ease as treatment goes on and are typically easy to manage with simple adjustments.
Serious side effects, such as seizures, are rare and occur at rates similar to standard TMS. Some data estimates a seizure risk of about 7 in 100,000 treatment sessions in traditional TMS. When seizures do occur, they’re usually brief—often under a minute—and don’t lead to lasting complications.
In accelerated TMS, “seizures are extremely uncommon when patients are properly screened,” says Dr. Hanlon. That’s why clinics must carefully evaluate patients with factors that could raise seizure risk, including certain medical conditions, substance use, or age-related considerations.
Clinics that provide TMS are also trained and equipped to manage seizures should they occur—another layer of safety built into care.
For the right person, accelerated TMS can be truly life-changing. In general, it’s safe and well tolerated, with side effect and seizure rates similar to standard TMS.
“Accelerated TMS can be a great option for adults with depression—especially if medications haven’t helped enough or caused unwanted side effects,” says Dr. Hanlon. In highly treatment-resistant cases, some studies have reported response rates as high as 90.5%, though others show results closer to standard daily TMS.
According to Dr. Hanlon, it’s also appealing for people who:
Because accelerated TMS works more quickly, it may be especially helpful for people who need rapid symptom relief, including:
On the flip side, accelerated TMS isn’t for everyone. “Some people may not be the best fit or may need extra screening first,” says Dr. Hanlon.
This includes individuals with:
“Pregnancy and other medical issues aren’t always deal breakers,” Dr. Hanlon adds, “but they should always be discussed with the treatment team.”
The best way to know if accelerated TMS is right for you is to talk with a trained provider who can review your history, assess risks, and answer your questions, says Dr. Hanlon. A personalized conversation is the safest place to start.

You’re not alone if “magnetic pulses to the brain” sounds intimidating—or like something out of a futuristic movie. Still, the reality is much less dramatic. Accelerated TMS is non-invasive and safe for most people. Here, Dr. Hanlon gives us a clear, no-mystery look at what a real SWIFT Deep TMS protocol session is like, so you know exactly what you’re walking into.
Because no two brains are the same, every accelerated TMS visit starts with personalization, says Dr. Hanlon.
Once that’s done, you’re ready to go.
With the SWIFT Deep TMS protocol, treatment happens in multiple quick sessions rather than one long stretch.
“The acute phase includes six half-day visits, which can be scheduled flexibly over a two-week period,” says Dr. Hanlon. After that comes a lighter follow-up phase: once a week for four weeks, with two sessions per visit (about 90 minutes total).
No anesthesia means no downtime. Most people feel well enough to drive themselves home, return to work, or go about their day right away.
This is where things get a little complicated (and expensive). Right now, insurance coverage is one of the biggest barriers to accelerated TMS. The good news: most major insurance companies do cover standard TMS and Deep TMS (though usually after someone has tried and not responded to multiple antidepressants), says Dr. Hanlon. The catch? There’s still “very limited insurance coverage for multiple sessions per day,” she says.
That said, momentum is building. Dr. Hanlon notes there’s been some encouraging progress with insurers, and coverage is likely to expand in the future. Some payers are beginning to consider accelerated TMS when traditional schedules haven’t worked, but approval depends heavily on your specific plan and medical necessity.
If insurance doesn’t cover it, brace yourself for a higher price tag. Accelerated TMS is pricey (typically costing between $17,000 and $23,000 for a course of treatment), reflecting the intensive schedule and staffing required. Costs can climb further if advanced tools are used. For example, the SAINT protocol relies on functional MRI to personalize targeting—an approach that may improve precision but also adds expense, notes Dr. Hanlon.
While the sticker shock is real, there may be options. Some clinics offer financial support to reduce the burden. Radial, for instance, provides financial hardship programs, accepts HSA/FSA cards, offers buy-now-pay-later options through partners like CareCredit and Wisetack, and can set up flexible payment plans when needed.
The gist: Accelerated TMS isn’t cheap, and insurance coverage is still catching up, but access is improving. If you’re interested, it’s worth asking both your provider and insurer about coverage options, alternatives, and payment plans that could make treatment more feasible.
Accelerated TMS is the new kid on the block. Standard TMS has been around for years, but accelerated versions are still rolling out, so you won’t find them at every clinic just yet.
A simple Google search for “accelerated TMS near me” can turn up clinics or hospital programs that offer it. If you’re specifically interested in SAINT TMS, Magnus Medical runs a locator tool (Radial clinics show up there, too). Another route? Clinical trials. Some people access accelerated TMS through open research studies.
Found a few options? Now it’s time to vet them. Not all accelerated TMS is the same, so asking the right questions matters. When you talk to a provider, consider asking:
Doing a little homework upfront can help you find the right clinic.
Accelerated TMS isn’t a magic fix, but it is a promising option for people who need relief sooner and haven’t found it with meds alone. By delivering a powerful, evidence-based treatment in a much shorter timeframe, it offers a new path forward for people stuck waiting weeks (or months) to feel better.
If you’re struggling with depression and wondering whether accelerated TMS could make sense for you, you don’t have to figure it out alone. Radial helps connect you with licensed clinicians—virtually or in person—who specialize in fast-acting, science-backed treatments and will work with you to build a personalized plan. When you’re ready to explore your options, Radial is here to help you take the next step.
Sadly, coverage is still limited. Most major insurers cover standard TMS and Deep TMS, but many don’t yet routinely cover multiple sessions per day, says Dr. Hanlon. Some plans may approve it on a case-by-case basis if standard treatments haven’t worked and medical necessity is documented. Coverage varies a lot by plan, so it’s worth asking a provider who can help you navigate prior authorization or alternatives.
Yes—accelerated TMS is generally very safe and well tolerated, with side effects similar to standard TMS. The most common ones are mild and temporary—things like scalp discomfort, headaches, facial muscle twitching, or feeling tired later in the day. Serious side effects, such as seizures, are rare, especially when patients are properly screened.
Yes—specific accelerated protocols are FDA-cleared. This includes approaches like SAINT TMS and BrainsWay’s SWIFT Deep TMS protocol for treatment-resistant depression. That said, not every accelerated schedule is FDA-cleared yet, and research is still evolving to determine the best dosing and delivery methods.
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