Research at Radial

Can targeted brain stimulation help when several severe, seemingly unrelated illnesses collide in one patient? This case report describes an individual with treatment-resistant PTSD, bipolar mania with psychosis, and psoriatic arthritis who achieved meaningful functional recovery after a course of multimodal noninvasive neuromodulation. Alongside marked psychiatric improvement, the patient's inflammatory joint symptoms also eased — pointing to possible shared mind-body pathways that brain stimulation may influence. Though based on a single case, the report suggests noninvasive neuromodulation could be worth exploring for complex, multimorbid presentations that resist conventional treatment.

Can AI reliably spot a movement disorder that clinicians routinely miss? This validation study found that an AI-powered video analysis model accurately detected tardive dyskinesia — a common side effect of long-term antipsychotic use — even when video recordings weren't collected under standardized conditions. The model showed strong agreement with expert clinician ratings and high diagnostic accuracy, suggesting it could support earlier, more consistent screening in real-world clinical settings.

Adolescents who self-harm or experience suicidal ideation are among the most challenging patients to engage therapeutically. This chapter presents the Mentalizing-Based Treatment framework for navigating these high-stakes clinical situations with structure, safety, and relational attunement.