Research at Radial

Backed by research.
Driven by care.

Radial clinicians don't just follow the research, they conduct it. From neuromodulation to digital psychiatry, our team actively publishes and participates in clinical trials, ensuring every patient receives care that is grounded in the best available evidence.

Featured publication

Mentalization-Based Treatment for Adolescents: The Framework for Work with Suicide and Self-Injurious Behaviors

Adolescents who self-harm or experience suicidal ideation are among the most challenging patients to engage therapeutically. This chapter presents the Mentalizing-Based Treatment framework for navigating these high-stakes clinical situations with structure, safety, and relational attunement.

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Trudie Rossouw, Owen Muir, Laurel L Williams
Adolescents who self-harm or experience suicidal ideation are among the most challenging patients to engage therapeutically. This chapter presents the Mentalizing-Based Treatment framework for navigating these high-stakes clinical situations with structure, safety, and relational attunement.
Recently in research
External Publications
June 2026

Functional Recovery After Multimodal Noninvasive Neuromodulation for Multimorbid PTSD, Bipolar Mania With Psychosis, and Psoriatic Arthritis

Muir O, Tendler A, Bermudes R
Can targeted brain stimulation help when several severe, seemingly unrelated illnesses collide in one patient? This case report describes an individual with treatment-resistant PTSD, bipolar mania with psychosis, and psoriatic arthritis who achieved meaningful functional recovery after a course of multimodal noninvasive neuromodulation. Alongside marked psychiatric improvement, the patient's inflammatory joint symptoms also eased — pointing to possible shared mind-body pathways that brain stimulation may influence. Though based on a single case, the report suggests noninvasive neuromodulation could be worth exploring for complex, multimorbid presentations that resist conventional treatment.
Clinical Trials
June 2026

Cross-Dataset Evaluation of an Automated Video-Based Model for Detecting Tardive Dyskinesia Using the Clinician's Tardive Inventory: Validation Study

Trosch R, Sterns A, Grimm B, Larsen L, Talbot B, Ma F, Ranjan R, MacMillan C, Hughes J, Friedman J, Muir O
Can AI reliably spot a movement disorder that clinicians routinely miss? This validation study found that an AI-powered video analysis model accurately detected tardive dyskinesia — a common side effect of long-term antipsychotic use — even when video recordings weren't collected under standardized conditions. The model showed strong agreement with expert clinician ratings and high diagnostic accuracy, suggesting it could support earlier, more consistent screening in real-world clinical settings.
External Publications
April 2026

Mentalization-Based Treatment for Adolescents: The Framework for Work with Suicide and Self-Injurious Behaviors

Trudie Rossouw, Owen Muir, Laurel L Williams
Adolescents who self-harm or experience suicidal ideation are among the most challenging patients to engage therapeutically. This chapter presents the Mentalizing-Based Treatment framework for navigating these high-stakes clinical situations with structure, safety, and relational attunement.

Publications

April 2026
Psychedelic Therapy
Psychedelic Therapy: A Primer for Primary Care Clinicians—Historical Perspective and Overview
Burton J Tabaac, Kenneth Shinozuka, Alejandro Arenas, Bryce D Beutler, Kirsten Cherian, Viviana D Evans, Chelsey Fasano, Owen S Muir
Psychedelic therapy didn't begin in research labs — it has a long, complex history worth understanding. This primer traces the historical foundations of psychedelic medicine, providing primary care clinicians with context for the current therapeutic renaissance.
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Psychedelic Therapy
April 2026
Psychedelic Therapy
Psychedelic Therapy: A Primer for Primary Care Clinicians—Psilocybin
Burton J Tabaac, Kenneth Shinozuka, Alejandro Arenas, Bryce D Beutler, Kirsten Cherian, Viviana D Evans, Chelsey Fasano, Owen S Muir
Psilocybin is arriving in clinical conversations faster than most primary care clinicians feel prepared for. This primer equips frontline providers with the evidence base, clinical context, and safety considerations needed to counsel patients meaningfully.
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Psychedelic Therapy
April 2026
Accelerated TMS
Real-world outcomes and predictors of accelerated rTMS treatment response for treatment-resistant depression
Danielle D DeSouza, Erica Nakano, Vivian Hoang, Kim Hoang, David Ling, Owen Muir, Nathan Meng, Noah DeGaetano, Shan H Siddiqi, David Carreon
Who responds to accelerated TMS in the real world — and what predicts success? This analysis of real-world treatment data identifies clinical and demographic factors associated with response, helping clinicians better match patients to this intensive protocol.
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Accelerated TMS
April 2026
Deep TMS
Accelerated Dtms Utilization Of H7 Coil For Comorbid Trd: A Case Series
Aslam MacMillan, Carlene MacMillan, Owen Muir
Treatment-resistant depression with comorbidities demands more than standard protocols. This case series examines the use of accelerated dTMS with the H7 coil in complex patients, documenting outcomes that support its use in harder-to-treat presentations.
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Deep TMS
April 2026
Mentalizing-Based Therapy
Basic Concepts in Mentalizing-Based Therapy for Emerging Personality Disorders
Laurel L Williams, Carl Fleisher, Owen S Muir, Chris Grimes, Carlene M MacMillan, Robert A Dugger
Personality difficulties in adolescence are often dismissed as a phase — but early intervention matters. This paper introduces core concepts of Mentalizing-Based Therapy for emerging personality disorders, equipping clinicians with a structured approach for younger patients.
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Mentalizing-Based Therapy
April 2026
Mentalizing-Based Therapy
Mentalizing-Based Therapy for Borderline Personality Disorder and Other “Difficult” Patients"
Laurel L Williams, Carl Fleisher, Efrain Bleiberg, Owen S Muir, Chris Grimes, Robert A Dugger
Borderline personality disorder in adolescents is frequently misunderstood and undertreated. This paper applies Mentalizing-Based Therapy to emerging personality disorders in teens, offering a developmentally grounded framework for clinicians working with this population.
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Mentalizing-Based Therapy
April 2026
Accelerated TMS
Cognitive changes and predictors of treatment outcome following accelerated rTMS treatment for depression
Kim Hoang, Laura Schulze, Erica Nakano, Vivian Hoang, David Ling, Shan Siddiqi, Owen Muir, Nate Meng, Noah DeGaetano, Danielle DeSouza, David Carreon
Can cognitive function predict who responds best to accelerated TMS? This study tracked cognitive changes before and after treatment, identifying baseline and post-treatment patterns that may help clinicians anticipate outcomes.
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Accelerated TMS
April 2026
Accelerated TMS
Impact of accelerated intermittent theta-burst stimulation on anxiety symptoms in major depressive disorder
Erica Nakano, Vivian Hoang, Kim Hoang, Laura Schulze, David Ling, Shan Siddiqi, Owen Muir, Nathan Meng, Noah DeGaetano, Danielle DeSouza, David Carreon
Depression and anxiety often travel together — so how well does accelerated TMS address both? This trial found that accelerated theta-burst stimulation produced meaningful reductions in anxiety symptoms alongside its established antidepressant effects.
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Accelerated TMS
April 2026
Accelerated TMS
Hourly mood assessments during accelerated rTMS for major depression: Trajectories of treatment response
Laura Schulze, Erica Nakano, Vivian Hoang, Kim Hoang, David Ling, Shan Siddiqi, Owen Muir, Nate Meng, Noah DeGaetano, Danielle DeSouza, David Carreon
When does relief actually begin during accelerated TMS — and can we track it hour by hour? This study used daily mood assessments to chart depression trajectories during treatment, revealing when and how quickly patients begin to respond.
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Accelerated TMS
April 2026
Psychedelic Therapy
Scaling Psychedelic Therapies in the Health System
B Traux, E Marseille, Owen Muir, J Glastra
Psychedelic therapies are moving from clinical trials into health systems — but the infrastructure isn't ready. This report outlines the policy, training, and operational frameworks needed to integrate psychedelic-assisted treatment at scale.
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Psychedelic Therapy
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Personality Disorders
Narcissism
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Mentalizing-Based Therapy
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Deep TMS
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Deep TMS
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Mentalizing-Based Therapy
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Mentalizing-Based Therapy
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Deep TMS
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AI / Digital Psychiatry
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Deep TMS
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Deep TMS
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Deep TMS
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Ketamine Monitoring
PTSD
Bipolar
TMS
Movement Disorders
AI / Digital Psychiatry
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Accelerated TMS
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AI / Digital Psychiatry
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Accelerated TMS
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Accelerated TMS
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TMS
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Psychedelic Therapy
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Psychedelic Therapy
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Psychedelic Therapy
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Psychedelic Therapy
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Psychedelic Therapy
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Psychedelic Therapy
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Psychedelic Therapy
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Psychedelic Therapy
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Deep TMS
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Mentalizing-Based Therapy
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Accelerated TMS
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Accelerated TMS
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Accelerated TMS
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Deep TMS
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Deep TMS
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Deep TMS
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Accelerated TMS
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Ketamine Therapy
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Active Clinical Trials

AI / Digital Psychiatry

Cross-Dataset Evaluation of an Automated Video-Based Model for Detecting Tardive Dyskinesia Using the Clinician's Tardive Inventory: Validation Study

Can AI reliably spot a movement disorder that clinicians routinely miss? This validation study found that an AI-powered video analysis model accurately detected tardive dyskinesia — a common side effect of long-term antipsychotic use — even when video recordings weren't collected under standardized conditions. The model showed strong agreement with expert clinician ratings and high diagnostic accuracy, suggesting it could support earlier, more consistent screening in real-world clinical settings.
View
Trosch R, Sterns A, Grimm B, Larsen L, Talbot B, Ma F, Ranjan R, MacMillan C, Hughes J, Friedman J, Muir O
Can AI reliably spot a movement disorder that clinicians routinely miss? This validation study found that an AI-powered video analysis model accurately detected tardive dyskinesia — a common side effect of long-term antipsychotic use — even when video recordings weren't collected under standardized conditions. The model showed strong agreement with expert clinician ratings and high diagnostic accuracy, suggesting it could support earlier, more consistent screening in real-world clinical settings.

Recent PR

Press

Postpartum OCD: Why New Parents Experience Frightening Intrusive Thoughts

Postpartum OCD can cause terrifying intrusive thoughts, compulsive checking, and intense fear after childbirth. Learn what's happening and how to get help.
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Leadership

Dr. Owen Scott Muir

Co-founder & Chief Medical Officer

MD, DFAACAP

Dual board-certified child, adolescent and adult psychiatrist, and author of the award-winning Frontier Psychiatrists newsletter and podcast

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Dr. Carlene MacMillan

Co-founder & Chief Product Officer

MD, FCTMSS, DFAACAP

Dual board-certified child, adolescent, and adult psychiatrist focused on expanding access to breakthrough treatments through better technology and insurance coverage advocacy.

Read more

John Capecelatro

CEO & Co-Founder

Elliot Cohen

Executive Chairman & Co-Founder

Stephanie Fillion

VP of Engineering

Jonathan Murray

Chief Commercial Officer

Leah Connor

VP of Operations

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