Research at Radial

Backed by research.
Driven by care.

Radial clinicians don't just follow the research, they conduct it. From neuromodulation to digital psychiatry, our team actively publishes and participates in clinical trials, ensuring every patient receives care that is grounded in the best available evidence.

Publications

Apr 2025
Ketamine Therapy
Mapping the Use of Ketamine in Treatment-Resistant Depression and Other Psychiatric Disorders: A Scoping Review of Practice Patterns, Efficacy, and Patient Demographic Trends
Amna M Aslam, Kenneth Shinozuka, Owen Muir, Burton J Tabaac
Ketamine has moved from operating rooms to psychiatric clinics — but how is it actually being used? This scoping review maps real-world ketamine practice patterns across treatment-resistant depression and other disorders, revealing wide variation in dosing, setting, and patient demographics.
Depression
Ketamine Therapy
Apr 2025
Accelerated TMS
Beyond the PHQ-9 and Into the DSM-XC: Transdiagnostic and Functional Assessment of Accelerated TMS Outcomes
Amna Aslam, Carlene MacMillan, Owen Muir
The PHQ-9 tells you a patient is depressed. But does it tell you enough? This paper examines accelerated TMS outcomes through a broader transdiagnostic lens, using DSM-5 criteria to capture functional recovery that symptom scales alone can miss.
Depression
Accelerated TMS
Apr 2025
Deep TMS
Resolution of Aphasia and Gait Instability in a Patient With HSV Encephalitis After dTMS Treatment: A Case Report
Amna Aslam, Owen Muir, Stephanie Sizemore, Irfan Handoo
A patient recovering from viral encephalitis loses the ability to speak and walk — then regains both after Deep TMS. This case report documents a striking recovery of aphasia and gait instability following dTMS treatment, suggesting potential neurorehabilitative applications.
Depression
Deep TMS
Apr 2025
Accelerated TMS
Assessing the Effectiveness of the SAINT® Neuromodulation System to Treat Major Depressive Disorder in a Real-World Setting: A Multisite, Open-Label Optimization Study
Hugh B Solvason, Roger Pottanat, Owen S Muir, Carlene MacMillan, Ian A Cook, David M Carreon, Robert Bota, Tracy Barbour, Rebecca M Allen, Katy Stimpson, Michael Feyder, TJ Ford, Nolan R Williams, Brandon S Bentzley
Real-world use of SAINT raises a critical question: does it hold up outside of controlled trials? This multisite open-label study confirms that the SAINT neuromodulation system produces meaningful antidepressant outcomes in community clinical settings.
Depression
Accelerated TMS
Apr 2025
Deep TMS
Safety and Efficacy of Deep TMS for Adolescent Depression: A Post-Marketing Surveillance Study
Yiftach Roth, Oluremi Adefolarin, Richard Bermudes, Mark Blair, Raymond Cho, Dianne Dekeyser, Raymond Garcia, Diana Ghelber, Steven Harvey, Kevin Kinback, Carlene MacMillan, Mah Mekolle, Owen Muir, Gabriel Pell, Teresa Poprawski, Alexander Rohr, Kevin Rosi, Jason Tripp, Aron Tendler, Colleen Hanlon
Adolescent depression demands safe, effective options — especially when medications fall short. This post-marketing surveillance study confirms that Deep TMS is well-tolerated and clinically effective for adolescents with treatment-resistant depression across real-world practice sites.
Depression
Deep TMS
Mar 2025
Psychedelic Therapy
Scaling Psychedelic Therapies in the Health System
B Traux, E Marseille, Owen Muir, J Glastra
Psychedelic therapies are moving from clinical trials into health systems — but the infrastructure isn't ready. This report outlines the policy, training, and operational frameworks needed to integrate psychedelic-assisted treatment at scale.
Depression
Psychedelic Therapy
Jan-Feb 2025
Accelerated TMS
Hourly mood assessments during accelerated rTMS for major depression: Trajectories of treatment response
Laura Schulze, Erica Nakano, Vivian Hoang, Kim Hoang, David Ling, Shan Siddiqi, Owen Muir, Nate Meng, Noah DeGaetano, Danielle DeSouza, David Carreon
When does relief actually begin during accelerated TMS — and can we track it hour by hour? This study used daily mood assessments to chart depression trajectories during treatment, revealing when and how quickly patients begin to respond.
Depression
Accelerated TMS
Jan-Feb 2025
Accelerated TMS
Impact of accelerated intermittent theta-burst stimulation on anxiety symptoms in major depressive disorder
Erica Nakano, Vivian Hoang, Kim Hoang, Laura Schulze, David Ling, Shan Siddiqi, Owen Muir, Nathan Meng, Noah DeGaetano, Danielle DeSouza, David Carreon
Depression and anxiety often travel together — so how well does accelerated TMS address both? This trial found that accelerated theta-burst stimulation produced meaningful reductions in anxiety symptoms alongside its established antidepressant effects.
Depression
Anxiety
Accelerated TMS
Jan-Feb 2025
Accelerated TMS
Cognitive changes and predictors of treatment outcome following accelerated rTMS treatment for depression
Kim Hoang, Laura Schulze, Erica Nakano, Vivian Hoang, David Ling, Shan Siddiqi, Owen Muir, Nate Meng, Noah DeGaetano, Danielle DeSouza, David Carreon
Can cognitive function predict who responds best to accelerated TMS? This study tracked cognitive changes before and after treatment, identifying baseline and post-treatment patterns that may help clinicians anticipate outcomes.
Depression
Accelerated TMS
Oct 2024
Mentalizing-Based Therapy
Mentalizing-Based Therapy for Borderline Personality Disorder and Other “Difficult” Patients"
Laurel L Williams, Carl Fleisher, Efrain Bleiberg, Owen S Muir, Chris Grimes, Robert A Dugger
Borderline personality disorder in adolescents is frequently misunderstood and undertreated. This paper applies Mentalizing-Based Therapy to emerging personality disorders in teens, offering a developmentally grounded framework for clinicians working with this population.
Personality Disorders
Mentalizing-Based Therapy
OCD
Deep TMS
Personality Disorders
Narcissism
Mentalizing-Based Therapy
Personality Disorders
Mentalizing-Based Therapy
Depression
Deep TMS
Depression
Deep TMS
Personality Disorders
Mentalizing-Based Therapy
Personality Disorders
Mentalizing-Based Therapy
Depression
Deep TMS
Movement Disorders
AI / Digital Psychiatry
OCD
Deep TMS
Depression
Deep TMS
Depression
Deep TMS
Depression
Deep TMS
Depression
Ketamine Monitoring
PTSD
Bipolar
TMS
Movement Disorders
AI / Digital Psychiatry
Depression
Accelerated TMS
Movement Disorders
AI / Digital Psychiatry
Depression
Accelerated TMS
OCD
Deep TMS
Depression
Accelerated TMS
Depression
Anxiety
TMS
Depression
Psychedelic Therapy
Depression
Psychedelic Therapy
Depression
Psychedelic Therapy
Depression
Psychedelic Therapy
Depression
Psychedelic Therapy
Depression
Psychedelic Therapy
Depression
Psychedelic Therapy
Depression
Psychedelic Therapy
Depression
Deep TMS
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Mescaline
Personality Disorders
Mentalizing-Based Therapy
Depression
Accelerated TMS
Depression
Anxiety
Accelerated TMS
Depression
Accelerated TMS
OCD
Deep TMS
Depression
Deep TMS
Depression
Deep TMS
Depression
Accelerated TMS
Depression
Deep TMS
Depression
Accelerated TMS
Depression
Ketamine Therapy
Conditions
Treatments
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Active clinical trials

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Research team

Dr. Owen Scott Muir

Co-founder & Chief Scientific Officer

MD, DFAACAP

Dual board-certified child, adolescent and adult psychiatrist, and author of the award-winning Frontier Psychiatrists newsletter and podcast

Owen Scott Muir is a dual board-certified psychiatrist pioneering innovative treatments for depression, anxiety, and OCD. When medications and therapy alone aren't enough, he helps patients find hope through evidence-based interventional psychiatry.

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Amna Aslam

Applied Research Specialist

Amna M. Aslam, MBA, MSc, is the Applied Research Specialist at Radial Health and serves as Expert Faculty for the American Society of Ketamine Physicians, Psychotherapists & Practitioners (ASKP3). She provides strategic research expertise in clinical outcomes research, post-marketing evidence generation, and health economics, with a focus on translating real-world data into evidence that informs clinical standard practices, healthcare decision-making, and patient access to innovative neuropsychiatric therapies.


Amna’s work spans the design and oversight of real-world evidence and post-marketing studies, clinical outcomes and patient-reported outcomes, and health economics and outcomes research (HEOR) across interventional psychiatry and neurology. She has led numerous investigator-initiated studies, retrospective analyses, prospective observational studies, and scientific publications evaluating innovative neuropsychiatric therapies. Her expertise includes comparative effectiveness research and health economic evaluations, including cost-effectiveness (CEA), cost-utility (CUA), cost-benefit (CBA), budget impact, and quality-adjusted life year (QALY) analyses. She leverages advanced statistical methodologies using SAS, SPSS, and R to generate robust clinical, economic, and patient-centered evidence that informs value-based healthcare decision-making.


Amna earned her Master of Business Administration and Master of Science in Pharmacy Administration with a concentration in Health Economics and Outcomes Research from St. John's University. She previously contributed to research and market access initiatives at Fermata Health and has served as an Community Affairs and Constituent Laison at her local NYS AssemblyMembers Office. Moreover she has served as adjunct professor and graduate research and teaching assistant at St. John's University. Outside of work, Amna enjoys traveling, trying new restaurants, and learning about the intersection of government and healthcare.

Angelique Lucien

Research Coordinator

Angelique Lucien is a Research Coordinator at Radial, where she supports clinical research focused on advancing innovative treatments in psychiatry and brain health. Her work involves coordinating research studies, engaging participants throughout the research process, ensuring regulatory compliance, and contributing to the collection of high-quality clinical data that helps improve treatment outcomes.


With a strong interest in interventional psychiatry, neuroscience, and mental health research, Angelique is passionate about supporting studies that advance our understanding of psychiatric illness and improve treatment options for patients. She is dedicated to helping ensure that research participants have a positive and supportive experience throughout the research process.


Outside of work, Angelique enjoys traveling, spending time with family and friends, trying new restaurants, and staying active. She is driven by a curiosity about the brain and a commitment to improving the lives of individuals affected by mental illness through research and innovation.

Aleah Goodman

Clinical Research Coordinator & Care Navigator

Aleah Goodman is a Clinical Research Coordinator and Patient Care Navigator with research experience in cognitive psychology and behavioral neuroscience. Her work is driven by a deep interest in the relationship between cognition, mental health, and the development of novel psychiatric treatments. She is particularly drawn to understanding how individuals make sense of themselves and perceive their progress over time, and how these experiences can inform increasingly personalized approaches to treatment.

Aleah supports clinical research in interventional psychiatry, including studies on Transcranial Magnetic Stimulation (TMS) and emerging psychiatric medications and technologies. Drawing on her experience as an Interventional Psychiatry Technician and Patient Care Navigator, she focuses on treatment response and patient-reported outcomes across both real-world and research settings with the goal of translating scientific discoveries into meaningful improvements in patient care.

Nicolas Silva

Clinical Research Coordinator & Interventional Psychiatric Technician

Nicolas Silva is a Clinical Research Coordinator and Intervention Psychiatry Technician passionate about advancing mental health research and care.


He holds a degree in Psychological Sciences from the University of Connecticut and is currently pursuing a Master's in Clinical Social Work — driven by a genuine desire to meet people not just in the data, but in the clinic.

His research interests span two areas he finds deeply connected: the role of faith expression in mental health outcomes, and the expanding frontier of interventional psychiatry treatments such as TMS and Spravato. He believes that understanding what gives people meaning — alongside emerging, evidence-based treatments — is essential to advancing compassionate, whole-person care.

Outside of work, Nicolas finds expression through writing poetry and music, playing guitar, and staying active. Creativity and movement are how he stays grounded — and how he brings a little more humanity into everything he does.

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