Research at Radial

Backed by research.
Driven by care.

Radial clinicians don't just follow the research, they conduct it. From neuromodulation to digital psychiatry, our team actively publishes and participates in clinical trials, ensuring every patient receives care that is grounded in the best available evidence.

Research areas

Narcissism

Movement Disorders

Schizophrenia Spectrum Disorders

Bipolar

Personality Disorders

OCD

PTSD

Anxiety

Depression

Publications

Value
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Assessing the Effectiveness of the SAINT® Neuromodulation System to Treat Major Depressive Disorder in a Real-World Setting: A Multisite, Open-Label Optimization Study

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Apr 2025
Hugh B Solvason, Roger Pottanat, Owen S Muir, Carlene MacMillan, Ian A Cook, David M Carreon, Robert Bota, Tracy Barbour, Rebecca M Allen, Katy Stimpson, Michael Feyder, TJ Ford, Nolan R Williams, Brandon S Bentzley
Real-world use of SAINT raises a critical question: does it hold up outside of controlled trials? This multisite open-label study confirms that the SAINT neuromodulation system produces meaningful antidepressant outcomes in community clinical settings.
Depression
Accelerated TMS
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Safety and Efficacy of Deep TMS for Adolescent Depression: A Post-Marketing Surveillance Study

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Apr 2025
Yiftach Roth, Oluremi Adefolarin, Richard Bermudes, Mark Blair, Raymond Cho, Dianne Dekeyser, Raymond Garcia, Diana Ghelber, Steven Harvey, Kevin Kinback, Carlene MacMillan, Mah Mekolle, Owen Muir, Gabriel Pell, Teresa Poprawski, Alexander Rohr, Kevin Rosi, Jason Tripp, Aron Tendler, Colleen Hanlon
Adolescent depression demands safe, effective options — especially when medications fall short. This post-marketing surveillance study confirms that Deep TMS is well-tolerated and clinically effective for adolescents with treatment-resistant depression across real-world practice sites.
Depression
Deep TMS
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Scaling Psychedelic Therapies in the Health System

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Mar 2025
B Traux, E Marseille, Owen Muir, J Glastra
Psychedelic therapies are moving from clinical trials into health systems — but the infrastructure isn't ready. This report outlines the policy, training, and operational frameworks needed to integrate psychedelic-assisted treatment at scale.
Depression
Psychedelic Therapy
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Hourly mood assessments during accelerated rTMS for major depression: Trajectories of treatment response

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Jan-Feb 2025
Laura Schulze, Erica Nakano, Vivian Hoang, Kim Hoang, David Ling, Shan Siddiqi, Owen Muir, Nate Meng, Noah DeGaetano, Danielle DeSouza, David Carreon
When does relief actually begin during accelerated TMS — and can we track it hour by hour? This study used daily mood assessments to chart depression trajectories during treatment, revealing when and how quickly patients begin to respond.
Depression
Accelerated TMS
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Impact of accelerated intermittent theta-burst stimulation on anxiety symptoms in major depressive disorder

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Jan-Feb 2025
Erica Nakano, Vivian Hoang, Kim Hoang, Laura Schulze, David Ling, Shan Siddiqi, Owen Muir, Nathan Meng, Noah DeGaetano, Danielle DeSouza, David Carreon
Depression and anxiety often travel together — so how well does accelerated TMS address both? This trial found that accelerated theta-burst stimulation produced meaningful reductions in anxiety symptoms alongside its established antidepressant effects.
Depression
Anxiety
Accelerated TMS
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Cognitive changes and predictors of treatment outcome following accelerated rTMS treatment for depression

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Jan-Feb 2025
Kim Hoang, Laura Schulze, Erica Nakano, Vivian Hoang, David Ling, Shan Siddiqi, Owen Muir, Nate Meng, Noah DeGaetano, Danielle DeSouza, David Carreon
Can cognitive function predict who responds best to accelerated TMS? This study tracked cognitive changes before and after treatment, identifying baseline and post-treatment patterns that may help clinicians anticipate outcomes.
Depression
Accelerated TMS
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Mentalizing-Based Therapy for Borderline Personality Disorder and Other “Difficult” Patients"

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Oct 2024
Laurel L Williams, Carl Fleisher, Efrain Bleiberg, Owen S Muir, Chris Grimes, Robert A Dugger
Borderline personality disorder in adolescents is frequently misunderstood and undertreated. This paper applies Mentalizing-Based Therapy to emerging personality disorders in teens, offering a developmentally grounded framework for clinicians working with this population.
Personality Disorders
Mentalizing-Based Therapy
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Basic Concepts in Mentalizing-Based Therapy for Emerging Personality Disorders

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Oct 2024
Laurel L Williams, Carl Fleisher, Owen S Muir, Chris Grimes, Carlene M MacMillan, Robert A Dugger
Personality difficulties in adolescence are often dismissed as a phase — but early intervention matters. This paper introduces core concepts of Mentalizing-Based Therapy for emerging personality disorders, equipping clinicians with a structured approach for younger patients.
Personality Disorders
Mentalizing-Based Therapy
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Accelerated Dtms Utilization Of H7 Coil For Comorbid Trd: A Case Series

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Oct 2024
Aslam MacMillan, Carlene MacMillan, Owen Muir
Treatment-resistant depression with comorbidities demands more than standard protocols. This case series examines the use of accelerated dTMS with the H7 coil in complex patients, documenting outcomes that support its use in harder-to-treat presentations.
Depression
Deep TMS
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Real-world outcomes and predictors of accelerated rTMS treatment response for treatment-resistant depression

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May 2024
Danielle D DeSouza, Erica Nakano, Vivian Hoang, Kim Hoang, David Ling, Owen Muir, Nathan Meng, Noah DeGaetano, Shan H Siddiqi, David Carreon
Who responds to accelerated TMS in the real world — and what predicts success? This analysis of real-world treatment data identifies clinical and demographic factors associated with response, helping clinicians better match patients to this intensive protocol.
Depression
Accelerated TMS
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Psychedelic Therapy: A Primer for Primary Care Clinicians—Psilocybin

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Mar-Apr 2024
Burton J Tabaac, Kenneth Shinozuka, Alejandro Arenas, Bryce D Beutler, Kirsten Cherian, Viviana D Evans, Chelsey Fasano, Owen S Muir
Psilocybin is arriving in clinical conversations faster than most primary care clinicians feel prepared for. This primer equips frontline providers with the evidence base, clinical context, and safety considerations needed to counsel patients meaningfully.
Depression
Psychedelic Therapy
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Psychedelic Therapy: A Primer for Primary Care Clinicians—Historical Perspective and Overview

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Mar-Apr 2024
Burton J Tabaac, Kenneth Shinozuka, Alejandro Arenas, Bryce D Beutler, Kirsten Cherian, Viviana D Evans, Chelsey Fasano, Owen S Muir
Psychedelic therapy didn't begin in research labs — it has a long, complex history worth understanding. This primer traces the historical foundations of psychedelic medicine, providing primary care clinicians with context for the current therapeutic renaissance.
Depression
Psychedelic Therapy
OCD
Deep TMS
Personality Disorders
Narcissism
Mentalizing-Based Therapy
Personality Disorders
Mentalizing-Based Therapy
Depression
Deep TMS
Depression
Deep TMS
Personality Disorders
Mentalizing-Based Therapy
Personality Disorders
Mentalizing-Based Therapy
Depression
Deep TMS
Movement Disorders
AI / Digital Psychiatry
OCD
Deep TMS
Depression
Deep TMS
Depression
Deep TMS
Depression
Deep TMS
Depression
Ketamine Monitoring
PTSD
Bipolar
TMS
Movement Disorders
AI / Digital Psychiatry
Depression
Accelerated TMS
Movement Disorders
AI / Digital Psychiatry
Depression
Accelerated TMS
OCD
Deep TMS
Depression
Accelerated TMS
Depression
Anxiety
TMS
Depression
Psychedelic Therapy
Depression
Psychedelic Therapy
Depression
Psychedelic Therapy
Depression
Psychedelic Therapy
Depression
Psychedelic Therapy
Depression
Psychedelic Therapy
Depression
Psychedelic Therapy
Depression
Psychedelic Therapy
Depression
Deep TMS
Personality Disorders
Mentalizing-Based Therapy
Depression
Accelerated TMS
Depression
Anxiety
Accelerated TMS
Depression
Accelerated TMS
OCD
Deep TMS
Depression
Deep TMS
Depression
Deep TMS
Depression
Accelerated TMS
Depression
Deep TMS
Depression
Accelerated TMS
Depression
Ketamine Therapy
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